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NSC 12
Price range: 77 CAD through 301 CAD
Products Details
Product Description
– NSC 12 is an orally active pan-FGF trap that inhibits FGF-dependent tumor cell proliferation, angiogenesis, and metastasis.NSC 12 binds FGF2 and interferes with its interaction with FGFR1, but does not affect the ability of FGF2 to bind heparin or heparan sulfate proteoglycans (HSPGs), with potential antitumor activity.NSC 12 also organizes several other FGF isoforms to form the HSPG/FGF/FGFR ternary complex.
Web ID
– T36292
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H34F6O3
CAS Number
– 102586-30-1
Molecular Weight
– C24H34F6O3
Compound Purity
– 0.9951
SMILES
– C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@H](CC(C(F)(F)F)(C(F)(F)F)O)O)[H])[H]
Target
– PI3K
Pathway
– Tyrosine Kinase/Adaptors|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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