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Products Details
Product Description
– Mitoguazone (Methyl-GAG) is a selective S-adenosyl-methionine decarboxylase inhibitor that penetrates the blood-brain barrier and disrupts polyamine biosynthesis. Mitoguazone is a synthetic polycarbonyl derivative with anti-tumor activity that inhibits the integration of HIV DNA into cellular DNA in monocytes and macrophages, inducing apoptosis. Mitoguazone can be used to prevent acute leukemia, Hodgkin lymphoma and non-Hodgkin lymphoma.
Web ID
– T35617
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C5H12N8
References
– R Amlacher, et al. Influence of Leukemia P388 on the Pharmacokinetics of Mitoguazone in B6D2F1 Mice. Pharmazie. 1990 May;45(5):364-6.
CAS Number
– 459-86-9
Molecular Weight
– C5H12N8
Compound Purity
– 0.98
SMILES
– CC(C=NNC(N)=N)=N/NC(N)=N
Pathway
– Proteases/Proteasome|||Microbiology/Virology|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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