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Fraxetin
Price range: 67 CAD through 602 CAD
Products Details
Product Description
– Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a marked inhibitory effect on S.aureus proliferation. It increased the level of Nrf2/ARE, and HO-1, inhibit the formation of ROS, cytochrome c release, activation of caspase-3 and 9, and suppressed the up-regulation of Bax.
Web ID
– T2909
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C10H8O5
Citations
– 1. Chen J, Zhou X, Fu L, et al.Natural Product-Based Screening for Lead Compounds Targeting SARS CoV-2 Mpro[J]. Pharmaceuticals, 2023, 16(5): 767..Pharmaceuticals.2023, 16(5): 767.
2. Weng M, Deng Z, Huang S, et al.Fraxetin inhibits proliferation and induces apoptosis of bladder cancer through the Akt pathway in vitro and in vivo.Journal of Biochemical and Molecular Toxicology.2023: e23556.
References
– Wang H, et al. Mol Med Rep. 2014 Nov;10(5):2341-5.
CAS Number
– 574-84-5
Molecular Weight
– C10H8O5
Compound Purity
– 0.9976
SMILES
– COc1cc2ccc(=O)oc2c(O)c1O
Pathway
– Apoptosis
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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