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QO-58
131 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– QO-58 is a Kv7 channel opener with EC50 values of 7.0, 1.0, 5.2, 0.6 μM for Kv7.1, Kv7.2, Kv7.3/7.5, Kv7.4 respectively. QO-58 increases the pain threshold of neuropathic pain in a sciatic nerve CCI in vivo.
Web ID
– T28483
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H8Cl2F4N4O
References
– Zhang et al (2013) Modulation of Kv7 potassium channels by a novel opener pyrazolo[1,5-a]pyrimidin-7(4H)-one compound QO-58. Br.J.Pharmacol. 168 1030. PMID: 23013484.
CAS Number
– 1259536-62-3
Molecular Weight
– C18H8Cl2F4N4O
SMILES
– Fc1cc(c(Cl)nc1Cl)-c1cc(=O)n2nc(c(-c3ccccc3)c2[nH]1)C(F)(F)F
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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