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Products Details
Product Description
– Fascaplysin is a cyclin D kinase 4/ cyclin D1 inhibitor (IC50 = 0.35 μM). Fascaplysin induces caspase mediated crosstalk between autophagy and apoptosis through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells.
Web ID
– T27305
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H11ClN2O
References
– Mischitelli M, Jemaà M, Almasry M, Faggio C, Lang F. Triggering of Suicidal Erythrocyte Death by Fascaplysin. Cell Physiol Biochem. 2016;39(4):1638-47. doi: 10.1159/000447865. PubMed PMID: 27626793.
CAS Number
– 114719-57-2
Molecular Weight
– C18H11ClN2O
SMILES
– [Cl-].O=C1C2=C(C=CC=C2)[N+]2=C1C1=C(C=C2)C2=CC=CC=C2N1
Pathway
– Others
Product type
– Natural Product
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