IRAK4-IN-16
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IRAK4-IN-16

SKU T24174-25 mg Category Brand:

Price range: 2,432 CAD through 4,000 CAD

Products Details

Product Description

– IRAK4-IN-16 (compound 4) is a potent inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with an IC50 of 2.5 nM. It exhibits cytotoxicity against OCI-LY10, TMD8, Ramos, and HT cells, with IC50 values of 0.2, 0.2, 0.6, and 2.7 μM, respectively [1].

Web ID

– T24174

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H20F2N8O

References

– Cheng BY, Lau EY, Leung HW, Leung CO, Ho NP, Gurung S, Cheng LK, Lin CH, Lo RC, Ma S, Ng IO, Lee TK. IRAK1 augments cancer stemness and drug resistance via the AP-1/AKR1B10 signaling cascade in hepatocellular carcinoma. Cancer Res. 2018 Feb 26. pii: canres.2445.2017. doi: 10.1158/0008-5472.CAN-17-2445. [Epub ahead of print] PubMed PMID: 29483095.

CAS Number

– 1812188-83-2

Molecular Weight

– C17H20F2N8O

SMILES

– C(NC=1C(C(F)F)=NN(C)C1)(=O)C2=C3N(N=C2)C=CC(N[C@@H]4CCCNC4)=N3

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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