DBCO-NHCO-PEG4-amine
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DBCO-NHCO-PEG4-amine

SKU T15062-1 mg Category Brand:

Price range: 656 CAD through 5,552 CAD

Products Details

Product Description

– DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) [1].

Web ID

– T15062

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H37N3O6

References

– Spangler B, et al. Toward a Ferrous Iron-Cleavable Linker for Antibody-Drug Conjugates. Mol Pharm. 2018 May 7;15(5):2054-2059. .

CAS Number

– 1255942-08-5

Molecular Weight

– C29H37N3O6

SMILES

– O=C(NCCC(=O)N1C=2C=CC=CC2C#CC=3C=CC=CC3C1)CCOCCOCCOCCOCCN

Target

– CCR|||Parasite|||CXCR

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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