BETd-260

SKU T14550-1 mg Category Brand:

Price range: 211 CAD through 1,258 CAD

Products Details

Product Description

– BETd-260, a PROTAC linked by a Cereblon ligand and a BET ligand, has an inhibitory effect on BRD4 protein in leukemic cell lines.

Web ID

– T14550

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C43H46N10O6

References

– Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.

CAS Number

– 2093388-62-4

Molecular Weight

– C43H46N10O6

Compound Purity

– 0.9676

SMILES

– N(C1=C2C=3C(NC2=NC(C(NCCCCCC4=C5C(C(=O)N(C5)C6C(=O)NC(=O)CC6)=CC=C4)=O)=N1)=CC(=C(OC)C3)C=7C(C)=NOC7C)C=8N(CC)N=C(C8)C9CC9

Target

– Others

Pathway

– Chromatin/Epigenetic|||PROTAC

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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