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AZ1495
Price range: 142 CAD through 1,792 CAD
Products Details
Product Description
– AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL).
Web ID
– T14367
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H31N5O2
References
– Scott JS, et al. Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse Large B-Cell Lymphoma. J Med Chem. 2017 Dec 28;60(24):10071-10091.
CAS Number
– 2196204-23-4
Molecular Weight
– C21H31N5O2
Compound Purity
– 0.9881
SMILES
– C1CC(CCO1)c1c[nH]c2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c12
Target
– Autophagy|||Histone Methyltransferase
Pathway
– Immunology/Inflammation|||Cell Cycle/Checkpoint|||NF-κB
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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