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TC-S 7009
Price range: 102 CAD through 869 CAD
Products Details
Product Description
– TC-S 7009 is a potent and selective HIF-2α inhibitor (Kd: 81 nM) with significantly higher affinity for HIF-2α than HIF-1α (Kd >> 5μM). TC-S 7009 disrupts HIF-2α heterodimerization, reduces HIF-2α target gene expression, and diminishes DNA binding activity.
Web ID
– T17009
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C12H6ClFN4O3
References
– Scheuermann TH, et al. Allosteric inhibition of hypoxia inducible factor-2 with small molecules. Nat Chem Biol. 2013;9(4):271-276.
CAS Number
– 1422955-31-4
Molecular Weight
– C12H6ClFN4O3
Compound Purity
– 0.9971
SMILES
– [O-][N+](=O)c1c(Nc2cc(F)cc(Cl)c2)ccc2nonc12
Target
– Epigenetic Reader Domain
Pathway
– Angiogenesis|||Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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