Tauroursodeoxycholate dihydrate

SKU T16998-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 35  USD through 105  USD

Products Details

Product Description

– Tauroursodeoxycholate (TUDCA ,Taurolite) dihydrate is a water-soluble bile acid with endoplasmic reticulum stress inhibitory, mitochondrial stabilizing, and anti-apoptotic effects, which significantly reduces the expression of apoptotic molecules, such as Caspase-3 and Caspase-12, and inhibits ERK, reducing endoplasmic reticulum stress mediated cell death.

Web ID

– T16998

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H49NO8S

References

– Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK viaPKCα-mediated MKP-1 induction. Cardiovasc Res. 2011 Nov 1;92(2):307-16.

CAS Number

– 117609-50-4

Molecular Weight

– C26H49NO8S

Compound Purity

– 0.9982

SMILES

– C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCCS(=O)(O)=O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C[C@@H]3O)C.O.O

Target

– Apoptosis|||PERK

Pathway

– Proteases/Proteasome|||Metabolism|||Apoptosis|||MAPK

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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