ALLO-2

SKU T14188-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 93 CAD through 1,525 CAD

Products Details

Product Description

– ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.

Web ID

– T14188

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H12F3N5O

References

– Tao H, et al. Small molecule antagonists in distinct binding modes inhibit drug-resistant mutant of smoothened. Chem Biol. 2011 Apr 22;18(4):432-7.

CAS Number

– 1357350-60-7

Molecular Weight

– C18H12F3N5O

Compound Purity

– 0.9919

SMILES

– FC(F)(F)Oc1ccc(cc1)-c1ccnc(Nc2ccc3[nH]ncc3c2)n1

Target

– NF-κB|||Endogenous Metabolite

Pathway

– GPCR/G Protein|||Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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