SRT 2183

SKU T16932-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 74 CAD through 1,048 CAD

Products Details

Product Description

– SRT 2183 is a selective activator of Sirtuin-1 (SIRT1, EC1.5 : 0.36 μM).

Web ID

– T16932

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H24N4O2S

Citations

– 1. Qin Z, Fang X, Sun W, et al. Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity. Nature Immunology. 2022: 1-15

References

– Scuto A, et al. SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-κB/STAT3 complex to its promoter in malignant lymphoid cells. Cell Death Dis. 2013 May; 4(5): e635.

CAS Number

– 1001908-89-9

Molecular Weight

– C27H24N4O2S

Compound Purity

– 0.9786

SMILES

– O[C@@H]1CCN(Cc2csc3nc(cn23)-c2ccccc2NC(=O)c2ccc3ccccc3c2)C1

Target

– Others

Pathway

– DNA Damage/DNA Repair|||Apoptosis|||Chromatin/Epigenetic

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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