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Caspase-3-IN-1
$230 – $680
Products Details
Product Description
– Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM[1].
Web ID
– HY-136975
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C26H25N3O6S
References
– [1]Chu W, et al. N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies. J Med Chem. 2005 Dec 1;48(24):7637-47.
CAS Number
– 872254-32-5
Molecular Weight
– 507.56
Compound Purity
– 97.04
SMILES
– O=S(C1=CC=C(C(C(C2=O)=O)=C1)N2CC3=CC=C(C=C3)OC)(N4[C@@H](CCC4)COC5=CN=CC=C5)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Caspase
Isoform
– Caspase 1;Caspase 3;Caspase 6;Caspase 7;Caspase 8
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
