PD 407824

SKU T16446-2 mg Category Brand:

157 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).

Web ID

– T16446

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H12N2O3

References

– Palmer BD, et al. 4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione inhibitors of the checkpoint kinase WeeStructure-activity relationships for chromophore modification and phenyl ring substitution. J Med Chem. 2006 Aug 10;49(16):4896-911.

CAS Number

– 622864-54-4

Molecular Weight

– C20H12N2O3

Compound Purity

– 0.9802

SMILES

– Oc1ccc2[nH]c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1

Target

– ADC Linker

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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