GNE-955
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GNE-955

SKU T15406-25 mg Category Brand:

Price range: 3,152 CAD through 5,440 CAD

Products Details

Product Description

– GNE-955 is a potent and orally active inhibitor of pan Pim kinase, with inhibition constants (Kis) of 0.018 nM, 0.11 nM, and 0.08 nM for Pim1, Pim2, and Pim3, respectively.

Web ID

– T15406

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H24N8O

References

– Wang X, et al. Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized Bioavailability. J Med Chem. 2017 May 25;60(10):4458-4473.

CAS Number

– 1527523-39-2

Molecular Weight

– C22H24N8O

SMILES

– O(C)C=1C(=NC(N2C=3C(C=N2)=CN=C(C3)C4=NC(C)=CN=C4)=CC1)N5C[C@@H](N)CCC5

Target

– Others

Pathway

– Chromatin/Epigenetic|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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