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PROTAC Bcl-xL degrader-3
$1,420 – $14,525
Products Details
Product Description
– PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader (WO2020163823A2, compound 44)[1].
Web ID
– HY-132997
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C82H105ClF3N11O11S4
CAS Number
– 2471970-60-0
Molecular Weight
– 1641.49
SMILES
– O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)NC(CCCCCCC(N(CC4)CCN4C[C@@](C)(C5)CCC(C6=CC=C(C=C6)Cl)=C5CN7CCN(C8=CC=C(C=C8)C(NS(=O)(C9=CC(S(C(F)(F)F)(=O)=O)=C(C=C9)N[C@@H](CSC%10=CC=CC=C%10)CCN%11CCOCC%11)=O)=O)CC7)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family;PROTACs
Isoform
– Bcl-xL;von Hippel-Lindau (VHL)
Pathway
– Apoptosis;PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
