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SMAP-2
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .
Web ID
– T12934
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H27F3N2O4S
References
– Sangodkar J, et al. Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth. J Clin Invest. 2017 Jun 1;127(6):2081-2090.
CAS Number
– 1809068-70-9
Molecular Weight
– C27H27F3N2O4S
SMILES
– O[C@@H]1[C@H](CCC[C@H]1N1c2ccccc2CCc2ccccc12)NS(=O)(=O)c1ccc(OC(F)(F)F)cc1
Target
– Akt
Pathway
– Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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