BAY-85-8501

SKU T12613L-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 141 CAD through 1,840 CAD

Products Details

Product Description

– BAY-85-8501 is a selective, reversible, and potent inhibitor of Human Neutrophil Elastase (HNE) with an IC50 of 65 pM.

Web ID

– T12613L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H17F3N4O3S

References

– Von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73.

CAS Number

– 1161921-82-9

Molecular Weight

– C22H17F3N4O3S

Compound Purity

– 0.9916

SMILES

– CN1[C@@H](C(C#N)=C(C)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1S(C)(=O)=O)C#N

Target

– Others

Pathway

– Proteases/Proteasome

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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