Tirabrutinib hydrochloride

SKU T12311-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 590 CAD

Products Details

Product Description

– Tirabrutinib hydrochloride is a potent, highly selective, and irreversible oral BTK inhibitor. Tirabrutinib hydrochloride irreversibly covalently binds to Bruton tyrosine kinase (BTK) in B cells and exhibits potent in vitro cytotoxicity against many types of B cell malignancies, as well as in vivo antitumor activity in mouse models [1].

Web ID

– T12311

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H23ClN6O3

References

– Akintunde Akinleye et al. Ibrutinib and novel BTK inhibitors in clinical development. J Hematol Oncol, 2013, 6: 59.

CAS Number

– 1439901-97-9

Molecular Weight

– C25H23ClN6O3

Compound Purity

– 0.9927

SMILES

– Cl.CC#CC(=O)N1CC[C@H](C1)n1c2ncnc(N)c2n(-c2ccc(Oc3ccccc3)cc2)c1=O

Target

– Others

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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