K145
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K145

SKU T11739-25 mg Category Brand:

Price range: 2,672 CAD through 4,480 CAD

Products Details

Product Description

– K145 is inactive against SphK1 and other protein kinases. K145 induces cell apoptosis and has potently antitumor activity. K145 is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM.

Web ID

– T11739

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H24N2O3S

References

– Liu K, et al. Biological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agent. PLoS One. 2013;8(2):e56471.

CAS Number

– 1309444-75-4

Molecular Weight

– C18H24N2O3S

SMILES

– C(CN)N1C(=O)C(=CCCC2=CC=C(OCCCC)C=C2)SC1=O

Target

– Others

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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