Download Files:
JBJ-02-112-05
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– JBJ-02-112-05 is a potent, mutant-selective, allosteric, and orally active inhibitor of EGFR, with an IC50 of 15 nM for EGFR L858R/T790M [1].
Web ID
– T11713
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H20N4O2S
References
– To C, et al. Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor. Cancer Discov. 2019 Jul;9(7):926-943.
CAS Number
– 2748162-29-8
Molecular Weight
– C27H20N4O2S
SMILES
– C(C(NC1=NC=CS1)=O)(N2C(=O)C=3C(C2)=CC=C(C3)C=4C=C5C(=CC4)NC=C5)C6=CC=CC=C6
Target
– ADC Linker
Pathway
– Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Stem Cells
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
1000 in stock
