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Products Details
Product Description
– HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC50 of 0.41 μM, capable of eliminating statins-induced accumulation of HMGCR, lowering serum cholesterol levels, and decreasing atherosclerosis [1].
Web ID
– T11572
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C33H54O3
References
– Jiang SY, et al. Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol. Nat Commun. 2018 Dec 3;9(1):5138.
CAS Number
– 2416941-68-7
Molecular Weight
– C33H54O3
SMILES
– C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(CC=C)(CC=C)O)C)(CC4)[H])[H])([C@@H](O)C=C1C(C)(C)[C@@H](O)CC2)[H])[H]
Target
– Others
Pathway
– Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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