GSK3368715 dihydrochloride

SKU T11500L-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 90 CAD through 150 CAD

Products Details

Product Description

– GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active and potent inhibitor of type I protein arginine methyltransferases (PRMTs), including PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8. It exhibits anticancer and antitumor activity and can be used to study advanced solid tumors.

Web ID

– T11500L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H40Cl2N4O2

References

– Fedoriw A, et al. Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss. Cancer Cell. 2019 Jul 8;36(1):100-114.e25.

CAS Number

– 1628925-77-8

Molecular Weight

– C20H40Cl2N4O2

Compound Purity

– 0.9966

SMILES

– Cl.Cl.CCOCC1(COCC)CCC(CC1)c1n[nH]cc1CN(C)CCNC

Target

– PDE

Pathway

– Chromatin/Epigenetic

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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