Nifedipine
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Nifedipine

SKU T1146-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 72 CAD through 85 CAD

Products Details

Product Description

– Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents.

Web ID

– T1146

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H18N2O6

Citations

– 1. Wang B, Pei J, Zhang H, et al.Dihydropyridine-derived calcium channel blocker as a promising anti-hantavirus entry inhibitor.Interventions for emerging infectious diseases.2023, 16648714. 2. Cui S, Suo N, Yang Y, et al.The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation.Acta Pharmacologica Sinica.2023: 1-12. 3. Li T, Wan Z, Wang Q, et al.Utilizing Tissues Self‐Assembled in Fiber Optic‐Based “Chinese Guzheng Strings” for Contractility Sensing and Drug Efficacy Evaluation: A Practical Approach.Small.2406144

References

– Ding Y, et al. J Pharmacol Exp Ther,2000, 292(2), 606-609.

CAS Number

– 21829-25-4

Molecular Weight

– C17H18N2O6

Compound Purity

– 0.9949

SMILES

– COC(=O)C1=C(C)NC(C)=C(C1C1=C(C=CC=C1)[N+]([O-])=O)C(=O)OC

Target

– Adenosine Receptor

Pathway

– Autophagy|||Neuroscience|||Membrane transporter/Ion channel|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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