GNE-1858

SKU T11438-1 mg Category Brand:

Price range: 280 CAD through 5,264 CAD

Products Details

Product Description

– GNE-1858 is an ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor (IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA).

Web ID

– T11438

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H26F2N8

References

– Wu P, et al. Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer. Structure. 2019 Jan 2;27(1):125-133.e4.

CAS Number

– 2680616-96-8

Molecular Weight

– C21H26F2N8

Compound Purity

– 0.987

SMILES

– CC(C)n1ncc2cnc(Nc3cc(nc(n3)N3CCC(F)(F)C3)C3CCNC3)cc12

Target

– TRP/TRPV Channel

Pathway

– MAPK

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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