EP4 receptor antagonist 1
Add to CompareAdded to Compare

Download Files:

EP4 receptor antagonist 1

SKU T11211-1 mg Category Brand:

Price range: 171 CAD through 661 CAD

Products Details

Product Description

– EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and 16.2 nM, respectively, while displaying minimal activity (IC50s >10 μM) against human EP1, EP2, and EP3 receptors.

Web ID

– T11211

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H21F3N4O3

References

– Yang JJ, et al. Discovery and Characterization of 1H-1,2,3-Triazole Derivatives as Novel Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy. J Med Chem. 2020 Jan 23;63(2):569-590.

CAS Number

– 2287259-07-6

Molecular Weight

– C23H21F3N4O3

Compound Purity

– 0.9953

SMILES

– CC=Cc1nnn(Cc2ccc(cc2)C(F)(F)F)c1C(=O)N[C@@H](C)c1ccc(cc1)C(O)=O

Target

– P2X Receptor

Pathway

– GPCR/G Protein|||Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
Mecarbinate
Mecarbinate Price range: 46 CAD through 56 CAD
1 g1 mL * 10 mM (in DMSO)

1000 in stock

Select options
Mephenesin
Mephenesin Price range: 53 CAD through 173 CAD
1 g10 g5 g

1000 in stock

Select options
Atenolol Hydrochloride
Atenolol Hydrochloride Price range: 2,432 CAD through 4,000 CAD
100 mg25 mg50 mg

1000 in stock

Add to cart
Methylene Blue trihydrate
Methylene Blue trihydrate 58 CAD

1000 in stock

Select options
7-Chloro-4-(piperazin-1-yl)quinoline
7-Chloro-4-(piperazin-1-yl)quinoline Price range: 56 CAD through 77 CAD
100 mg200 mg

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });