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(E/Z)-BCI
Price range: 117 CAD through 1,888 CAD
Products Details
Product Description
– (E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signaling axis and inhibiting the NF-κB pathway.
Web ID
– T11139
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H23NO
References
– Zhang F, et al. DUSP6 Inhibitor (E/Z)-BCI Hydrochloride Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Murine Macrophage Cells via Activating the Nrf2 Signaling Axis and Inhibiting the NF-κB Pathway. Inflammation. 2019 Apr;42(2):672-681.
CAS Number
– 15982-84-0
Molecular Weight
– C22H23NO
Compound Purity
– 0.9994
SMILES
– O=C1C(=Cc2ccccc2)C(NC2CCCCC2)c2ccccc12
Target
– Endogenous Metabolite|||Vitamin
Pathway
– Apoptosis|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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