CM-675
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CM-675

SKU T10841-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 93 CAD through 1,229 CAD

Products Details

Product Description

– CM-675 is a dual inhibitor of phosphodiesterase 5 (PDE5) and class I histone deacetylases (IC50s: 114 nM and 673 nM for PDE5 and HDAC1) with the potential to treat Alzheimer’s disease.

Web ID

– T10841

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H32N6O3

References

– Rabal O, et al. Discovery of in Vivo Chemical Probes for Treating Alzheimer’s Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors. ACS Chem Neurosci. 2019 Mar 20;10(3):1765-1782.

CAS Number

– 1872466-47-1

Molecular Weight

– C31H32N6O3

Compound Purity

– 0.9967

SMILES

– CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(Cc2ccc(cc2)C(=O)Nc2ccccc2N)ccc1OCC

Target

– PROTACs

Pathway

– Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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