Ceranib-2

SKU T10761-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 75 CAD through 821 CAD

Products Details

Product Description

– Ceranib-2 (3-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-4-phenyl-1H-quinolin-2-one) is an inhibitor of ceramidase with an IC50 of 28 μM in SKOV3 cells. Ceranib-2 decreases levels of sphingosine and S1P, induces cell apoptosis and exhibits anticancer activity.

Web ID

– T10761

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H19NO3

References

– Draper JM, et al. Discovery and evaluation of inhibitors of human ceramidase. Mol Cancer Ther. 2011 Nov;10(11):2052-61.

CAS Number

– 1402830-75-4

Molecular Weight

– C25H19NO3

Compound Purity

– 0.9849

SMILES

– COc1ccc(C=CC(=O)c2c(-c3ccccc3)c3ccccc3[nH]c2=O)cc1

Target

– PDE

Pathway

– Apoptosis|||GPCR/G Protein

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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