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β-Nicotinamide mononucleotide
$38 – $144
Products Details
Product Description
– β-nicotinamide mononucleotide (β-NM) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of β-nicotinamide mononucleotide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer’s disease, and complications associated with obesity[1].
Web ID
– HY-F0004
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C11H15N2O8P
References
– [1]Poddar SK, et al. Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule. Biomolecules. 2019;9(1):34. Published 2019 Jan 21.|[2]Lv H, et al. NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion [published online ahead of print, 2020 Nov 3]. Cell Metab. 2020;S1550-4131(20)30554-4.|[3]Li J, et al. p53 prevents doxorubicin cardiotoxicity independently of its prototypical tumor suppressor activities. Proc Natl Acad Sci U S A. 2019;116(39):19626-19634.|[4]Yoshino J, et al Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536.
CAS Number
– 1094-61-7
Molecular Weight
– 334.22
Compound Purity
– 99.68
SMILES
– NC(C1=C[N+]([C@@H]2O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]2O)=CC=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– H2O : 83.33 mg/mL (ultrasonic)
Target
– Endogenous Metabolite
Isoform
– Human Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
