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Products Details
Product Description
– Zinterol (MJ 9184) is a potent and selective β2-adrenoceptor agonist[1]. Zinterol increases ICa in a concentration-dependent manner with an EC50 of 2.2 nM[2].
Web ID
– HY-14304
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H26N2O4S
References
– [1]Gwee MC, et al. Pharmacological actions of a new -adrenoceptor agonist, MJ-9184-1, in anaesthetized cats. Br J Pharmacol. 1972 Nov;46(3):375-85.|[2]Skeberdis VA, et al. Beta-2 adrenergic activation of L-type Ca<sup>2+</sup> current in cardiac myocytes. J Pharmacol Exp Ther. 1997 Nov;283(2):452-61.|[3]Desantiago J, et al. Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca load. Circ Res. 2008 Jun 6;102(11):1389-97.
CAS Number
– 37000-20-7
Molecular Weight
– 378.49
SMILES
– CS(=O)(NC1=CC(C(O)CNC(C)(C)CC2=CC=CC=C2)=CC=C1O)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– H2O : 1.89 mg/mL (ultrasonic)
Target
– Adrenergic Receptor
Isoform
– β adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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