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Zinc Pyrithione
$55 – $119
Products Details
Product Description
– Zinc Pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump[1]. Zinc Pyrithione is also a copper ionophore that delivers copper into cells and is a useful tool for studying cuproptosis[2].
Web ID
– HY-B0572
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C10H8N2O2S2Zn
References
– [1]Ermolayeva, E. and D. Sanders, Mechanism of pyrithione-induced membrane depolarization in Neurospora crassa. Appl Environ Microbiol, 1995. 61(9): p. 3385-90.|[2]Peter Tsvetkov, et al. Copper induces cell death by targeting lipoylated TCA cycle proteins. Science. 2022 Mar 18;375(6586):1254-1261.
CAS Number
– 13463-41-7
Molecular Weight
– 317.69
Compound Purity
– 99.49
SMILES
– N12[O-][Zn+2]3([S]=C1C=CC=C2)[O-]N(C=CC=C4)C4=[S]3
Clinical Information
– Launched
Research Area
– Infection; Metabolic Disease
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)|H2O : 0.1 mg/mL (ultrasonic)
Target
– Bacterial;Fungal;Proton Pump
Pathway
– Anti-infection;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
