Zinc Protoporphyrin

SKU T13396-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 67 CAD through 376 CAD

Products Details

Product Description

– Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active, competitive inhibitor of heme oxygenase-1 (HO-1) that markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 and exhibits anti-cancer activity.

Web ID

– T13396

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C34H32N4O4Zn

Citations

– 1. Qiu W, An S, Wang T, et al. Melatonin suppresses ferroptosis via activation of the Nrf2/HO-1 signaling pathway in the mouse model of sepsis-induced acute kidney injury. International Immunopharmacology. 2022, 112: 109162.

References

– Park C, et al. Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosisthrough Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes. Mar Drugs. 2019 Apr 13;17(4).

CAS Number

– 15442-64-5

Molecular Weight

– C34H32N4O4Zn

Compound Purity

– 0.9927

SMILES

– CC1=C(CCC(O)=O)C2=NC1=C/c1c(C=C)c(C)c3C=C4/N=C(/C=c5/c(C)c(CCC(O)=O)c(=C2)n5[Zn]n13)C(C)=C4C=C

Target

– Prostaglandin Receptor

Pathway

– Apoptosis|||Metabolism|||Immunology/Inflammation|||NF-κB

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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