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Zicronapine (fumarate)
SKU
HY-14827A-Get quote
Category Reference compound
Tags 5-HT Receptor;Dopamine Receptor, GPCR/G Protein;Neuronal Signaling, Neurological Disease
Products Details
Product Description
– Zicronapine (Lu 31-130) fumarate is an antipsychotic medication with a strong pro-cognitive effect in animal models and the potential to treat a number of neurological and psychiatric diseases. Zicronapine (Lu 31-130) fumarate has potent antagonistic effects at dopamine D1/D2, and serotonin 5-HT2A receptors[1][2].
Web ID
– HY-14827A
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H31ClN2O4
References
– [1]Lopez De Diego, Heidi. et al. Succinate and malonate salts of trans-4-(1R,3S)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and their preparation, pharmaceutical compositions, and use as medicaments, particularly as antipsychotics. WO2005016900A1|[2]Lundbeck H. A/S. The clinical phase III programme commenced on zicronapine. 20 Jan 2011.
CAS Number
– 170381-17-6
Molecular Weight
– 470.99
SMILES
– O=C(O)/C=C/C(O)=O.CC1(C)N(C)CCN([C@@H]2C[C@@H](C3=CC=CC=C3)C4=C2C=C(Cl)C=C4)C1
Clinical Information
– Phase 3
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor;Dopamine Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.