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ZAPA (sulfate)
SKU
HY-100799-Get quote
Category Reference compound
Tags GABA Receptor, Membrane Transporter/Ion Channel;Neuronal Signaling, Neurological Disease
Products Details
Product Description
– ZAPA sulfate is an agonist at low affinity GABAA-receptors. ZAPA sulfate induces membrane hyperpolarization of the Ascaris muscle cell with an EC50 of 10.3 μM[1][2].
Web ID
– HY-100799
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C4H8N2O6S2
References
– [1]Yokogawa T, et al. Analysis of GABAA‐and GABAB‐receptor mediated effects on intracellular Ca2+ in DRG hybrid neurones. British journal of pharmacology, 2001, 134(1): 98-107.|[2]Holden-Dye L, et al. ZAPA, (Z)-3-[(aminoiminomethyl)thio]-2-propenoic acid hydrochloride, a potent agonist at GABA-receptors on the Ascaris muscle cell. Br J Pharmacol. 1988 Sep;95(1):3-5.
CAS Number
– 371962-01-5
Molecular Weight
– 244.25
SMILES
– O=C(O)/C=CSC(N)=N.O=S(O)(O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.