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Products Details
Product Description
– ZAPA sulfate is an agonist at low affinity GABAA-receptors. ZAPA sulfate induces membrane hyperpolarization of the Ascaris muscle cell with an EC50 of 10.3 μM[1][2].
Web ID
– HY-100799
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C4H8N2O6S2
References
– [1]Yokogawa T, et al. Analysis of GABAA‐and GABAB‐receptor mediated effects on intracellular Ca2+ in DRG hybrid neurones. British journal of pharmacology, 2001, 134(1): 98-107.|[2]Holden-Dye L, et al. ZAPA, (Z)-3-[(aminoiminomethyl)thio]-2-propenoic acid hydrochloride, a potent agonist at GABA-receptors on the Ascaris muscle cell. Br J Pharmacol. 1988 Sep;95(1):3-5.
CAS Number
– 371962-01-5
Molecular Weight
– 244.25
SMILES
– O=C(O)/C=CSC(N)=N.O=S(O)(O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
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