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Z-Ile-Leu-aldehyde
$200 – $600
Products Details
Product Description
– Z-Ile-Leu-aldehyde (Z-IL-CHO) is a potent and competitive peptide aldehyde inhibitor of γ-secretase and notch[1][2].
Web ID
– HY-12465
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H30N2O4
References
– [1]Reem Suleiman, et al. The Role Of Notch In Th17 Differentiation. University of Massachusetts Amherst. 9-2013.|[2]Schwarzer R, et al. Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model. Blood Cancer J. 2014 Jun 13;4:e217.
CAS Number
– 161710-10-7
Molecular Weight
– 362.46
Compound Purity
– 98.0
SMILES
– O=C(OCC1=CC=CC=C1)N[C@H](C(N[C@H](C=O)CC(C)C)=O)[C@@H](C)CC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 41 mg/mL
Target
– Apoptosis;Notch;γ-secretase
Pathway
– Apoptosis;Neuronal Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
