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Products Details
Product Description
– YT 6-2 analog-1 (compound 2-3) serves as an autophagy-targeting ligand (ATL) aimed at p62/SQSTM1, useful in synthesizing the AUTOTAC degrader ATC-324 for the Androgen Receptor (AR). ATC-324 promotes the formation of AR/p62 complexes, leading to the autophagic-lysosomal degradation of AR. It effectively reduces nuclear AR levels, downregulates the expression of AR and AR-v7 target genes, and can degrade common AR mutants found in prostate cancer (PCa).
Web ID
– T203234
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H20F2O4
CAS Number
– 2409960-12-7
Molecular Weight
– C23H20F2O4
SMILES
– O(CC1=CC=C(F)C=C1)C2=C(OCC3=CC=C(F)C=C3)C=CC(OC[C@H]4CO4)=C2
Target
– PARP
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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