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Yoda 1
Price range: 62 CAD through 2,336 CAD
Products Details
Product Description
– Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1 (EC50=17.1/26.6 μM). Yoda 1 is also an inhibitor of glycine transporter protein 2 (GlyT2).
Web ID
– T7506
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H8Cl2N4S2
Citations
– 1. Zheng Q, Zou Y, Teng P, et al. Mechanosensitive Channel PIEZO1 Senses Shear Force to Induce KLF2/4 Expression via CaMKII/MEKK3/ERK5 Axis in Endothelial Cells. Cells. 2022, 11(14): 2191
2. Chen L, Yan Y, Kong F, et al. Contribution of Oxidative Stress Induced by Sonodynamic Therapy to the Calcium Homeostasis Imbalance Enhances Macrophage Infiltration in Glioma Cells. Cancers. 2022, 14(8): 2036
References
– Ruhma S , Jie X , Dubin A E , et al. Chemical activation of the mechanotransduction channel Piezo1[J]. eLife, 2015, 4.
CAS Number
– 448947-81-7
Molecular Weight
– C13H8Cl2N4S2
Compound Purity
– 0.9998
SMILES
– Clc1cccc(Cl)c1CSc1nnc(s1)-c1cnccn1
Pathway
– Membrane transporter/Ion channel
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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