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YKL-06-061
SKU
HY-120056-10 mg
Category Reference compound
Tags Immunology/Inflammation, Inflammation/Immunology, Salt-inducible Kinase (SIK)
$88 – $891
Products Details
Product Description
– YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1].
Web ID
– HY-120056
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C30H37N7O2
References
– [1]Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184.
CAS Number
– 2172617-15-9
Molecular Weight
– 527.66
Compound Purity
– 99.89
SMILES
– O=C1N(C2=NC(NC3=CC=C(C=C3OC)N4CCN(CC4)C)=NC=C2CN1C5=C(C=CC=C5C)C)C6CCC6
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 16.67 mg/mL (ultrasonic)
Target
– Salt-inducible Kinase (SIK)
Isoform
– SIK1
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.