YKL-06-061

$88$891

Products Details

Product Description

– YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1].

Web ID

– HY-120056

Storage Temperature

– -20°C (Powder, protect from light, stored under nitrogen)

Shipping

– Blue Ice

Applications

– COVID-19-immunoregulation

Molecular Formula

– C30H37N7O2

References

– [1]Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184.

CAS Number

– 2172617-15-9

Molecular Weight

– 527.66

Compound Purity

– 99.89

SMILES

– O=C1N(C2=NC(NC3=CC=C(C=C3OC)N4CCN(CC4)C)=NC=C2CN1C5=C(C=CC=C5C)C)C6CCC6

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 16.67 mg/mL (ultrasonic)

Target

– Salt-inducible Kinase (SIK)

Isoform

– SIK1

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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