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Products Details
Product Description
– XY028-140 is a selective CDK4/CDK6 degrade and inhibits both CDK4/6 expression and activity in cancer cells. XY028-140 is a PROTAC connected by ligands for Cereblon and CDK.
Web ID
– T36694
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C39H40N10O7
References
– Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WO2018106870A1.
CAS Number
– 2229974-83-6
Molecular Weight
– C39H40N10O7
Compound Purity
– 0.9859
SMILES
– O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)N4CCN(C(CNC5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5)=O)CC4)N2)C8CCCC8
Pathway
– PROTAC|||Cell Cycle/Checkpoint
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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