XY028-140

SKU T36694-1 mg Category Brand:

Price range: 54 CAD through 1,005 CAD

Products Details

Product Description

– XY028-140 is a selective CDK4/CDK6 degrade and inhibits both CDK4/6 expression and activity in cancer cells. XY028-140 is a PROTAC connected by ligands for Cereblon and CDK.

Web ID

– T36694

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C39H40N10O7

References

– Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WO2018106870A1.

CAS Number

– 2229974-83-6

Molecular Weight

– C39H40N10O7

Compound Purity

– 0.9859

SMILES

– O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)N4CCN(C(CNC5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5)=O)CC4)N2)C8CCCC8

Pathway

– PROTAC|||Cell Cycle/Checkpoint

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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