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Products Details
Product Description
– XST-14 is a competitive and specific inhibitor of ULK1 (IC50: 26.6 nM).XST-14 blocks autophagy by inhibiting the phosphorylation of ULK1 downstream substrates.XST-14 induces apoptosis and inhibits the growth of HCC cells.
Web ID
– T60604
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C16H21NO4
References
– Si-Tu Xue, et al. The role of the key autophagy kinase ULK1 in hepatocellular carcinoma and its validation as a treatment target . Autophagy. 2020 Oct;16(10):1823-1837.
CAS Number
– 2607143-50-8
Molecular Weight
– C16H21NO4
Compound Purity
– 0.9984
SMILES
– COC(=O)c1cc2c(OC(C)C)cc(OC(C)C)cc2[nH]1
Pathway
– Apoptosis|||Autophagy
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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