Products Details

Product Description

– XPW1 is a potent and selective CDK9 inhibitor with excellent activity against clear cell renal cell carcinoma (ccRCC) and low toxicity[1].

Web ID

– HY-149673

Shipping

– Room temperature

Molecular Formula

– C36H39ClFN7O2

References

– [1]Kuang Z, et al. The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma. Br J Cancer. 2023 Oct 26.

CAS Number

– 2700286-66-2

Molecular Weight

– 656.19

SMILES

– O=C(N[C@H]1CC[C@H](NC2=NC=C(Cl)C(C3=NC(NCC4=CC=CC(F)=C4)=CC=C3)=C2)CC1)C5=CC=C(NC(/C=C/CN(C)C)=O)C=C5

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– CDK

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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