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XL388
Price range: 61 CAD through 1,146 CAD
Products Details
Product Description
– XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.
Web ID
– T6030
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H22FN3O4S
Citations
– 1. Wang Z, Feng J, Yu J, et al. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. Journal of Cell Science. 2019, 132(10): jcs227777
2. Chen C, Zhang X, Wang Y, et al. Translational and Post-translational Control of Human Naïve versus Primed Pluripotency. iScience. 2021: 103645.
References
– Nicole Miller, et al. Mol Cancer Ther, 2009, 8(12 Suppl):B146.
CAS Number
– 1251156-08-7
Molecular Weight
– C23H22FN3O4S
Compound Purity
– 0.9939
SMILES
– Cc1c(F)c(ccc1C(=O)N1CCOc2ccc(cc2C1)-c1ccc(N)nc1)S(C)(=O)=O
Pathway
– PI3K/Akt/mTOR signaling|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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