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Products Details
Product Description
– Xanthine oxidase-IN-6 (Compound 6c) is a potent, orally active, mixed-type xanthine oxidase (XOD) inhibitor with an IC50 value of 1.37 µM. Xanthine oxidase-IN-6 shows strong anti-hyperuricemia and renal protective activity[1].
Web ID
– HY-146560
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C29H34N2O15
References
– [1]Jia-shu Chen, et al. Synthesis and biological evaluation of geniposide derivatives as inhibitors of hyperuricemia, inflammatory and fibrosis. Eur J Med Chem. 2022 Apr 20;237:114379.
Molecular Weight
– 650.58
SMILES
– [H][C@]12CC=C([C@]1(C(OC=C2C(NC3=NC=CO3)=O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4OC(C)=O)OC(C)=O)OC(C)=O)COC(C)=O)[H])COC(C)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NF-κB;TNF Receptor;Toll-like Receptor (TLR);Xanthine Oxidase
Isoform
– CD40;NF-κB;TLR4
Pathway
– Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
