WZ4002

SKU T6238-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 824 CAD

Products Details

Product Description

– WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.

Web ID

– T6238

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H27ClN6O3

Citations

– 1. Jin X, Yang Y, Liu D, et al.Identification of a covalent NEK7 inhibitor to alleviate NLRP3 inflammasome-driven metainflammation.Cell Communication and Signaling.2024, 22(1): 565.

References

– Zhou W, et al. Nature. 2009, 462(7276), 1070-1074.

CAS Number

– 1213269-23-8

Molecular Weight

– C25H27ClN6O3

Compound Purity

– 0.9812

SMILES

– O(C)C=1C=C(C=CC1NC=2N=C(OC3=CC(NC(C=C)=O)=CC=C3)C(Cl)=CN2)N4CCN(C)CC4

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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