WYE-687
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WYE-687

SKU T6732-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 184 CAD

Products Details

Product Description

– WYE-687 is an ATP-competitive and selective inhibitor of mTOR with an IC50 of 7 nM; it blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) without affecting P-AKT(T308). Its selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold).

Web ID

– T6732

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H32N8O3

References

– Yu K, et al, Cancer Res, 2009, 69(15), 6232-6240.

CAS Number

– 1062161-90-3

Molecular Weight

– C28H32N8O3

Compound Purity

– 0.9898

SMILES

– COC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(C3CCN(Cc4cccnc4)CC3)c2n1

Pathway

– MAPK|||Angiogenesis|||PI3K/Akt/mTOR signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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