WYE-132
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WYE-132

SKU T6346-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 693 CAD

Products Details

Product Description

– WYE-125132 (WYE-132 (WYE-125132)) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.

Web ID

– T6346

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H33N7O4

Citations

– 1. Wang Z, Feng J, Yu J, et al. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. Journal of Cell Science. 2019, 132(10): jcs227777

References

– Yu K, et al. Cancer Res. 2010, 70(2), 621-631.

CAS Number

– 1144068-46-1

Molecular Weight

– C27H33N7O4

Compound Purity

– 0.9916

SMILES

– CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C3CCC4(CC3)OCCO4)c2n1

Pathway

– PI3K/Akt/mTOR signaling|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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