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Product Description
– WWL0245 is a potent and selective BRD4-targeting PROTAC that exhibits sub-nanomolar degradation efficiency (DC50 1 μM). It demonstrates pronounced selective cytotoxicity in BETi-sensitive cancer cell lines, particularly in AR-positive prostate cancer lines, making it a promising candidate for research in AR-positive prostate cancer and a valuable tool for the investigation of BRD4’s biological function [1].
Web ID
– T79065
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C45H51N11O8
CAS Number
– 2869057-11-2
Molecular Weight
– C45H51N11O8
SMILES
– C(N1C=2C(N3C([C@H]1CC)=NN=C3C)=CN=C(NC4=C(OC)C=C(C(NC5CCN(C(COC6=C7C(C(=O)N(C7=O)C8C(=O)NC(=O)CC8)=CC=C6)=O)CC5)=O)C=C4)N2)C9CCCCC9
Pathway
– Chromatin/Epigenetic
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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