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WNK1-IN-1

$200$1,750

Products Details

Product Description

– WNK1-IN-1 is a selective inhibitor of WNK1 with an IC50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer[1].

Web ID

– HY-151545

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C13H15BrCl2N2O4S

References

– [1]Rodriguez M, et al. Synthesis and Structural Characterization of Novel Trihalo-sulfone Inhibitors of WNK1. ACS Med Chem Lett. 2022 Sep 23;13(10):1678-1684.

CAS Number

– 324022-39-1

Molecular Weight

– 446.14

Compound Purity

– 99.40

SMILES

– O=[N+](C1=CC(S(=O)(C(Cl)(Br)Cl)=O)=CC=C1NC2CCCCC2)[O-]

Clinical Information

– No Development Reported

Research Area

– Cancer; Cardiovascular Disease

Target

– Ser/Thr Protease

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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